Palatal Osteotomy

Palatal osteotomy is a surgical technique that creates a controlled cut through the hard palate to reposition portions of the upper jaw, helping correct skeletal and dental relationships. During the procedure, the surgeon separates the palatal bone and associated maxillary segments, adjusts their position to improve transverse width or occlusion, and stabilizes them while bone healing occurs. It is used in selected orthognathic and craniofacial surgeries, including correction of maxillary discrepancies that cannot be treated predictably with orthodontics alone. Careful planning helps preserve the palatal mucosa, tooth roots, blood supply, and functional outcomes.

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Research

JoVE EoE - Rodent Models

Dissection of Palate Tissue from Adult Murine Model: A Surgical Procedure to Harvest Hard Palate and Soft Palate from Oral Cavity of Adult Mouse

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2025

This video demonstrates a surgical procedure to dissect the palate tissue from a murine model.

Live Imaging of Mouse Secondary Palate Fusion

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Cited by 11 •

2017

Here, we present a protocol for live imaging of mouse secondary palate fusion using confocal microscopy. This protocol can be used in combination with a variety of fluorescent reporter mouse lines, and with pathway inhibitors for mechanistic insight. This protocol can be adapted for live imaging in other developmental systems.

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

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Cited by 10 •

2016

This protocol describes an osteosynthesis technique using an intramedullary locking nail for standardized fixation of femur osteotomies, which can be used to analyze normal and defective bone healing in mice.

Method of Studying Palatal Fusion using Static Organ Culture

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Cited by 6 •

2015

Studies of palate development are motivated by the incidence of cleft palate, a birth defect that imposes a tremendous health burden and can leave lasting disfigurement. We demonstrate here a technique to culture palatal shelves that can be used to study different signaling pathways involved in palatal development and fusion.

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

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Cited by 19 •

2014

One constraint of preclinical research in the field of bone repair is the lack of experimental control over the local mechanical environment within a healing bone lesion. We report the design and use of an external fixator for bone repair with the ability to change fixator stiffness in vivo.

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