Parotid Gland Injection

Parotid gland injection is a medical procedure that delivers medication into the parotid salivary gland to treat disorders involving excessive saliva production, gland inflammation, or localized dysfunction. Clinicians identify the gland and its surrounding anatomy, then guide a needle to the target tissue; when botulinum toxin is injected, it blocks acetylcholine release from parasympathetic nerve terminals, reducing stimulation of saliva-producing cells. The procedure can help manage sialorrhea associated with neurological disease and other conditions while limiting systemic treatment effects. Accurate anatomical localization and careful technique are essential because the parotid gland lies near the facial nerve, major blood vessels, and the external ear canal.

Parotid Gland Injection - Related Videos

Research

JoVE EoE - Immunotherapy

An Ultrasound-Guided Injection of Therapeutic Drugs into Human Salivary Glands

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2025

The video demonstrates an ultrasound-guided injection technique for administering therapeutic drugs into the salivary glands of a human patient.

Intraductal Injection: Delivering Injection Mix into the Ducts of the Mouse Mammary Gland

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2023

This video describes an intraductal injection technique where we deliver injection mix into the ducts of mouse mammary glands.

Research

JoVE Journal - Biology
Free Sample

Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland

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Cited by 36 •

2013

A protocol for the non-invasive intraductal delivery of aqueous reagents to the mouse mammary gland is described. The method takes advantage of localized injection into the nipples of mammary glands targeting mammary ducts specifically. This technique is adaptable for a variety of compounds including siRNA, chemotherapeutic agents and small molecules.

Rabbit Intraductal Injection: Localized Delivery of Solution of Interest into the Rabbit Mammary Gland

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2023

In this video we describe a technique of administering a solution of interest into the mammary duct of a rabbit and confirm the delivery by high-resolution ultrasound imaging of contrast agents.

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea

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Cited by 21 •

2016

Botulinum toxin is injected into the salivary glands for the treatment of sialorrhea. The ultrasound-guided botulinum toxin injection in both the parotid and submandibular glands demonstrates a sustained efficacy and the absence of serious side effects.

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