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JoVE Journal
Biology

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Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland
 

Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland

Article doi: 10.3791/50692
October 4th, 2013 Usage Statistics

Summary October 4th, 2013

A protocol for the non-invasive intraductal delivery of aqueous reagents to the mouse mammary gland is described. The method takes advantage of localized injection into the nipples of mammary glands targeting mammary ducts specifically. This technique is adaptable for a variety of compounds including siRNA, chemotherapeutic agents and small molecules.

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