Perigenital Mechanical Sensitivity

Perigenital mechanical sensitivity is the ability of tissues and sensory nerves surrounding the genitals to detect and respond to physical forces such as pressure, touch, and stretch. Mechanoreceptors in the skin and deeper tissues convert these stimuli into nerve signals, which travel through peripheral and spinal pathways for interpretation by the nervous system; sensitivity can be shaped by inflammation, injury, hormonal state, and neural processing. In medicine, measuring perigenital mechanical sensitivity helps characterize normal sensory function and investigate altered sensation, including tenderness, numbness, or pain associated with pelvic and urogenital disorders.

Perigenital Mechanical Sensitivity - Related Videos

Research

JoVE Journal - Medicine

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

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Cited by 25 •

2015

We are measuring perigenital mechanical sensitivity and mast cell activation in the prostate of male C57BL/6 mice that underwent an early life stress paradigm – neonatal maternal separation, in order to induce a preclinical model of chronic prostatitis/chronic pelvic pain syndrome.

Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain

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Cited by 4 •

2022

To develop novel therapeutic interventions for the prevention and management of back pain, animal models are required to examine the mechanisms and effectiveness of these therapies from a translational perspective. The present protocol describes the BMS test, a standardized method to assess back mechanical sensitivity in the rat.

Data Acquisition Protocol for Determining Embedded Sensitivity Functions

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2016

The data acquisition procedure for determining embedded sensitivity functions is described. Data is acquired and representative results are shown for a residential scale wind turbine blade.

Education

JoVE Science Education - Chemistry

Dye-sensitized Solar Cells

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2023

Source: Tamara M. Powers, Department of Chemistry, Texas A&M University Today's modern world requires the use of a large amount of energy. While we harness energy from fossil fuels such as coal and oil, these sources are nonrenewable and thus the supply is limited. To maintain our global lifestyle, we must extract energy from renewable sources. The most promising renewable source, in terms of abundance, is the sun, which provides us with more than enough solar energy to fully fuel our...

Mechanical Stimulation of Chondrocyte-agarose Hydrogels

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Cited by 29 •

2012

The biosynthesis of cartilaginous extracellular matrix by chondrocytes can be affected by application of mechanical stimuli. This method describes the technique of applying dynamic compressive strains to chondrocytes encapsulated in 3D constructs and the evaluation of induced changes in chondrocyte metabolism.

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