Small Animal Ultrasound
Small Animal Ultrasound - Related Videos
14:20
High-frequency Ultrasound Imaging of the Abdominal Aorta
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2023
Source: Amelia R. Adelsperger, Evan H. Phillips, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana High-frequency ultrasound systems are used to acquire high resolution images. Here, the use of a state-of-the-art system will be demonstrated to image the morphology and hemodynamics of small pulsatile arteries and veins found in mice and rats. Ultrasound is a relatively inexpensive, portable, and versatile method for the noninvasive...
01:37
Non-invasive Monitoring and Imaging in Animal Research
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2026
All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Non-invasive technologies support the principles of 3Rs by enabling repeated data collection from the same animal without the need for euthanasia at multiple time points. These approaches reduce the number of animals required...
09:00
Murine Echocardiography and Ultrasound Imaging
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Cited by 61 •
2010
This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.
07:12
Diagnostic Ultrasound Imaging of Mouse Diaphragm Function
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Cited by 7 •
2014
Diagnostic ultrasound imaging has proven to be effective in diagnosing various respiratory diseases in human and animal subjects. We demonstrate a comprehensive ultrasound protocol utilized by Dr. Zuo's lab to analyze diaphragm kinetics specifically in mouse models. This is also a non-invasive research technique which can provide quantitative information on mouse respiratory muscle function.
10:02
High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
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Cited by 6 •
2015
This protocol describes the application of high-frequency ultrasound (HFUS) for imaging mouse cervical lymph nodes. This technique optimizes visualization and quantification of cervical lymph node morphology, volume and blood flow. Image-guided biopsy of cervical lymph nodes and processing of lymph tissue for histological evaluation is also demonstrated.
FAQs
The returning echo pattern changes when sound pulses encounter tissues with different density and acoustic impedance, meaning resistance to sound transmission. The transducer converts these echoes into visual differences that help distinguish organs, soft tissues, fluid, and abnormal structures. This relationship provides the image contrast needed to recognize masses, fluid accumulation, and organ abnormalities during examination.
Real-time imaging allows clinicians to observe organs and tissues as they are being examined rather than relying only on a static image. This dynamic capability is useful for evaluating the abdomen, heart, reproductive tract, and soft tissues, while also supporting monitoring over time. It can help clinicians relate visible structural changes to an animal’s current clinical condition.
A major distinction is that ultrasound produces images with high-frequency sound waves rather than ionizing radiation. This allows veterinary teams to examine companion animals through a noninvasive approach while viewing structures dynamically. The combination of portability and real-time visualization makes it particularly useful when clinicians need bedside assessment, repeated monitoring, or imaging during a guided procedure.
The examination centers on a transducer, which sends sound pulses into the animal and receives the returning echoes. The system converts those signals into real-time images of the selected body region. Depending on the clinical question, the same imaging process can assess organs, tissues, fluid, or the reproductive tract, and can guide needle biopsy procedures.
Veterinarians may select this technique when they need to examine abdominal organs, the heart, reproductive structures, or other soft tissues in a dog or cat. It can support investigation of fluid accumulation, masses, and organ abnormalities, as well as pregnancy assessment. Its noninvasive nature and dynamic display also make it useful for clinical diagnosis and ongoing monitoring.
Beyond displaying internal structures, ultrasound can guide needle biopsies and other procedures by providing real-time visual information about the target area. The technique also supports follow-up because clinicians can monitor visible organs, tissues, fluid, or abnormalities over time. In medicine, these capabilities connect imaging with both diagnostic decision-making and assessment of changing clinical findings.