Ventricular Tachycardia Ablation
Ventricular Tachycardia Ablation - Related Videos
06:57
Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
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2019
With the following protocol, we provide an approach to Ventricular Tachycardia (VT) ablation using high density mapping with a multipolar catheter and 3D mapping system enhancing the success of the procedure.
12:09
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
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Cited by 14 •
2013
A methodology to estimate ventricular fiber orientations from in vivo images of patient heart geometries for personalized modeling is described. Validation of the methodology performed using normal and failing canine hearts demonstrate that that there are no significant differences between estimated and acquired fiber orientations at a clinically observable level.
11:21
Robotic Ablation of Atrial Fibrillation
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Cited by 12 •
2015
Pulmonary vein isolation (PVI) with an ablation catheter is a curative treatment for atrial fibrillation (AF). Robotic catheter systems aim to improve catheter steerability. Here, a procedure with a new robotic catheter system is presented. The goal of the procedure is electrical block between pulmonary vein and left atrium.
09:36
Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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Cited by 1 •
2023
This protocol introduces dual-dye optical mapping of mouse hearts obtained from wild-type and knock-in animals affected by catecholaminergic polymorphic ventricular tachycardia, including electrophysiological measurements of transmembrane voltage and intracellular Ca2+ transients with high temporal and spatial resolution.
04:42
Targeted Neuronal Ablation Using Two-Photon Microscopy in a Zebrafish Larava
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2025
Source: Muto, A., et al. Ablation of a Neuronal Population Using a Two-photon Laser and Its Assessment Using Calcium Imaging and Behavioral Recording in Zebrafish Larvae. J. Vis. Exp. (2018) In this video, a two-photon laser ablation procedure is demonstrated, enabling the selective destruction of fluorescent neurons in agarose-immobilized zebrafish larvae. High-resolution imaging before and after the procedure confirms efficient neuronal damage, as observed by the absence of fluorescence.
FAQs
Mapping records the heart’s electrical behavior to locate either a reentrant circuit, meaning a pathway that sustains the rhythm, or a focal trigger that initiates it. This distinction helps the treatment team select the cardiac tissue responsible for ventricular tachycardia rather than applying lesions without a rhythm-based target. The result is a more individualized intervention.
Radiofrequency or cryothermal energy creates controlled lesions in selected tissue. Their purpose is to disrupt the electrical continuity of a sustaining circuit or eliminate a focal trigger identified during mapping. Because lesion placement is tied to the rhythm mechanism, the intervention aims at the source of abnormal ventricular activation and can reduce subsequent episodes.
Structural heart disease provides an important clinical context because abnormal ventricular rhythms may arise in hearts with altered tissue architecture. In these patients, mapping and imaging help relate electrical findings to the underlying cardiac structure. That information supports individualized targeting, particularly when ventricular tachycardia recurs or remains inadequately controlled with medication.
Cardiac imaging and three-dimensional mapping provide complementary views of the problem. Imaging contributes information about cardiac structure, while electrical mapping identifies the locations and patterns associated with ventricular tachycardia. Used together with individualized rhythm analysis, these tools help connect anatomy with abnormal electrical activity, improving the basis for selecting treatment targets during ablation.
The procedure begins with electrophysiologic mapping to identify the circuit or focal trigger sustaining ventricular tachycardia. The treatment team then applies radiofrequency or cryothermal energy to create controlled lesions in the selected cardiac tissue. The intervention is evaluated through clinically relevant outcomes, including arrhythmia burden, implantable cardioverter-defibrillator shocks, and hospitalization.
The approach is particularly relevant for patients with structural heart disease or recurrent ventricular tachycardia despite medication. In that setting, repeated arrhythmia episodes can make rhythm control difficult, while ablation offers a way to target the mapped circuit or trigger directly. Its clinical role is to reduce arrhythmia burden and related implantable cardioverter-defibrillator shocks and hospitalizations.
Success is judged by the clinical impact of the intervention, not solely by the fact that lesions were created. Important outcomes include fewer ventricular tachycardia episodes, a lower overall arrhythmia burden, reduced implantable cardioverter-defibrillator shocks, and fewer hospitalizations. These measures show whether rhythm control has improved for a patient whose arrhythmia was recurrent or difficult to manage.