Ventricular Wall Thickness
Ventricular Wall Thickness - Related Videos
07:24
Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
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Cited by 34 •
2013
This article describes procedures for implanting a novel hydrogel in failing hearts and quantifying its effect on left ventricular wall stress and function. These procedures have been successfully applied in dogs and humans.
08:22
Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart
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Cited by 13 •
2020
We present a protocol for the isolation of endocardial and coronary endothelial cells from rat hearts through sequential tissue digestion in a digestion buffer, cell collection from recurrent centrifuge cycles, and cell purification using anti-rat CD31 microbeads.
10:33
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
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Cited by 34 •
2014
Right ventricle (RV) dysfunction is critical to the pathogenesis of cardiovascular disease, yet limited methodologies are available for its evaluation. Recent advances in ultrasound imaging provide a noninvasive and accurate option for longitudinal RV study. Herein, we detail a step-by-step echocardiographic method using a murine model of RV pressure overload.
12:30
Glycan Profiling of Plant Cell Wall Polymers using Microarrays
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Cited by 26 •
2012
A technique called Comprehensive Microarray Polymer Profiling (CoMPP) for the characterisation of plant cell wall glycans is described. This method combines the specificity of monoclonal antibodies directed to defined glycan-epitopes with a miniature microarray analytical platform allowing screening of glycan occurrence in a broad range of biological contexts.
09:22
Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Cited by 22 •
2015
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.
FAQs
Sustained pressure overload can trigger myocardial hypertrophy, increasing ventricular wall thickness as muscle adapts to a persistent workload. This response reflects remodeling rather than an isolated measurement and should be considered alongside the ventricle’s chamber size and pumping performance. In medicine, that pattern can help characterize structural consequences of hypertension-related cardiac stress.
Reduced thickness may signal weakened or dilated ventricular muscle, but its significance depends on the rest of cardiac assessment. A thin wall is therefore not interpreted independently: clinicians relate it to chamber dimensions and pumping performance to determine whether remodeling is associated with impaired function. This context helps distinguish a structural finding from its functional consequences.
The measurement gains meaning when paired with chamber size and pumping performance because wall structure alone does not show how effectively the ventricle functions. Considering these findings together helps clinicians relate remodeling to cardiac performance, improving assessment of conditions such as hypertension-related heart disease, cardiomyopathy, or congenital abnormalities.
Echocardiography and cardiac magnetic resonance imaging are named clinical tools for assessing ventricular wall thickness, with other imaging methods also available. Their role is to document ventricular structure in patients being evaluated for remodeling, hypertension-related heart disease, cardiomyopathy, or congenital abnormalities. Imaging findings can then contribute to diagnosis, risk assessment, treatment planning, and monitoring.
Assessment is most useful when the measurement is integrated into a broader cardiac evaluation rather than considered alone. Clinicians combine wall thickness with chamber size and pumping performance, then use the overall pattern to support diagnosis and risk assessment. The same framework also informs treatment planning and helps track whether structural disease changes over time.
In congenital abnormalities, clinicians use the measurement as one part of structural assessment. It can help document ventricular remodeling and support diagnosis or risk assessment, while chamber size and pumping performance provide necessary context. This approach avoids treating a single thickness value as a complete description of congenital cardiac function.