Auditory Brainstem Response

Auditory Brainstem Response (ABR) is an electrophysiological test that records the brain’s automatic response to sound, providing a noninvasive measure of auditory pathway function. During the procedure, brief clicks or tone bursts stimulate the ear while scalp electrodes detect synchronized neural activity as it travels from the cochlea through the auditory nerve and brainstem. The resulting waveform contains distinct peaks whose timing and amplitude reflect signal transmission through these structures. In neuroscience and clinical research, ABR supports hearing assessment, newborn screening, evaluation of auditory pathway disorders, and studies of how the brainstem processes sound, often when behavioral responses cannot be reliably measured.

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Measuring the Auditory Brainstem Response in Mice

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2025

Source: Lee, D., et. al. Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage. J. Vis. Exp. (2023)This video demonstrates the measurement of auditory brainstem response (ABR) in a mouse. Electrodes are placed on the head, behind the ear, and near the tail of an anesthetized mouse. Acoustic stimuli at various intensities are delivered, and electric signals generated are recorded as waveforms.

Recording Auditory Brainstem Responses in a Rat Pup

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2025

This video demonstrates a method for recording auditory brainstem responses (ABRs) from rat pups. It outlines the steps for electrode placement, sound stimulus application, and signal processing analysis in the brainstem to assess neural responses.

Recording Electrically-Evoked Auditory Brainstem Responses in a Deafened Mouse

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2025

This video demonstrates the procedure to implant a cochlear device in a deafened mouse and apply electrical stimuli to record auditory brainstem responses. This procedure enables to understand the basic mechanisms of electrical hearing and can contribute to advancements in cochlear implant technology and auditory neuroscience.

In Ovo Electroporation in the Chicken Auditory Brainstem

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Cited by 6 •

2017

Auditory brainstem neurons of avians and mammals are specialized for fast neural encoding, a fundamental process for normal hearing functions. These neurons arise from distinct precursors of embryonic hindbrain. We present techniques utilizing electroporation to express genes in the hindbrain of chicken embryos to study gene function during auditory development.

Preparation and Culture of Chicken Auditory Brainstem Slices

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Cited by 17 •

2011

The chicken auditory brainstem is comprised of nuclei responsible for binaural sound processing. A single coronal slice preparation maintains the entire circuitry while the cultured approach provides a unique preparation to study the development of neuronal structure and auditory function at the molecular, cellular and network levels.

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