Biopolymer-coated Plate

A biopolymer-coated plate is a laboratory vessel whose surface is covered with a biologically derived polymer to modify cell interactions and support controlled in vitro experiments. The coating changes surface chemistry, often improving the attachment, spreading, and maintenance of cells by providing a more compatible interface than untreated plastic. In neuroscience, these plates help researchers culture neurons and other neural cells, examine cellular morphology and behavior, and evaluate responses to experimental conditions. By promoting more consistent cell growth and organization, biopolymer-coated plates improve the reproducibility of studies involving neural development, cellular signaling, neurotoxicity, and disease modeling.

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Research

JoVE Journal - Chemistry
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Preparation of Biopolymer Aerogels Using Green Solvents

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Cited by 44 •

2016

A new way for the production of biopolymer-based aerogels by carbon dioxide (CO2) induced gelation is shown. The technique utilizes pressurized carbon dioxide (5 MPa) for the production of biopolymer hydrogels and supercritical CO2 (12 MPa) to convert gels into aerogels. The only solvents needed besides CO2 are water and ethanol.

Research

JoVE Journal - Bioengineering

Methods for the Self-integration of Megamolecular Biopolymers on the Drying Air-LC Interface

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Cited by 4 •

2017

A method for the drying-induced self-integration of megamolecular biopolymers on the air-liquid crystalline interface is provided here. This methodology will be useful not only for understanding the macroscopic potentials of biopolymers, but also as an evaluation method for soft materials in biomedical and environmental fields.

Thermally Responsive Biopolymer-Based Inhibition of Tumor Progression in a Rat Model

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2025

Begin with an anesthetized rat bearing a brain tumor composed of proliferating tumor cells.Expose the rat’s skull and create a hole to reveal the brain region with the tumor.Take a thermally responsive biopolymer fused with a cell-penetrating peptide and an inhibitor of c-myc, an oncogenic protein.Inject the biopolymer into the femoral vein of the hind limb for delivery to the brain.Apply infrared light through the skull hole to heat the tumor site, which induces biopolymer aggregation along...

Molecular Entanglement and Electrospinnability of Biopolymers

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Cited by 13 •

2014

Electrospinning is a fascinating technique used to fabricate micro- to nano-scale fibers from a wide variety of materials. Molecular entanglement of the constituent polymers in the spinning dope is essential for successful electrospinning. We present a protocol for utilizing rheology to evaluate the electrospinnability of two biopolymers, starch and pullulan.

Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology

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Cited by 24 •

2016

Synthesis schemes to prepare highly stable wood fiber-based hairy nanoparticles and functional cellulose-based biopolymers have been detailed.

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