H1 Neuron

The H1 neuron is a motion-sensitive visual neuron found in the blowfly brain and is a classic model for studying how nervous systems detect movement. It integrates signals from many photoreceptors and visual interneurons, responding selectively to wide-field horizontal motion while showing reduced activity or inhibition for motion in the opposite direction. Because its direction-selective responses can be recorded and linked to specific visual stimuli, the H1 neuron has helped researchers connect sensory input with neural coding and behavioral responses. Studies of H1 support broader investigations of motion perception, neural computation, synaptic integration, and the organization of sensory pathways.

H1 Neuron - Related Videos

Research

JoVE Journal - Behavior
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How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression

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Cited by 13 •

2017

The H1 deep transcranial magnetic stimulation coil is FDA-cleared for the treatment of depression. We demonstrate how to utilize the H1 for other conditions, such as auditory hallucinations and PTSD, by moving the helmet to different locations over the subject's skull.

Research

JoVE Journal - Behavior
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Treating Clinical Depression with Repetitive Deep Transcranial Magnetic Stimulation Using the Brainsway H1-coil

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Cited by 3 •

2016

Here we present a protocol outlining the methodology for treatment of Major Depressive Disorder using the deep Transcranial Magnetic Stimulation (dTMS) system.

Research

JoVE Journal - Neuroscience
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Inducing Plasticity of Astrocytic Receptors by Manipulation of Neuronal Firing Rates

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Cited by 8 •

2014

Here we describe an adaptation of protocols used to induce homeostatic plasticity in neurons for the study of plasticity of astrocytic G protein-coupled receptors. Recently used to examine changes in astrocytic group I mGluRs in juvenile mice, the method can be applied to measure scaling of various astrocytic GPCRs, in tissue from adult mice in situ and in vivo, and to gain a better appreciation of the sensitivity of astrocytic receptors to changes in neuronal activity.

Research

JoVE EoE - Neuronal Culture Techniques

Direct Neuronal Reprogramming of Mouse Astrocytes into Neurons

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2025

This video showcases the direct reprogramming of astrocytes expressing transforming factors into neurons. Transformation factors trigger a cascade of molecular events facilitating astrocyte-to-neuron conversion. The process is further supported by supplying specific agents and supplements through a neuronal differentiation medium.

Immunohistochemical Staining of B7-H1 (PD-L1) on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

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Cited by 43 •

2013

B7-H1 (PD-L1) and its binding to PD-1 provide a major tumor-induced immunosuppressive signal in the tumor’s microenvironment. An immunohistochemical staining technique to characterize the expression and localization of B7-H1 in pancreatic adenocarcinoma is described here.

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