Silicon Probe Recording
Silicon Probe Recording - Related Videos
17:37
Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents
0 Views •
Cited by 111 •
2012
We describe methods for large-scale recording of multiple single units and local field potential in behaving rodents with silicon probes. Drive fabrication, probe attachment to the drive and probe implantation processes are illustrated in sufficient details for easy replication.
05:45
Recording Large-scale Neuronal Ensembles with Silicon Probes in the Anesthetized Rat
0 Views •
Cited by 24 •
2011
Extracellular recordings of neuronal activity using silicon probes in the anesthetized rat will be described. This technique allows information to be obtained across multiple brain areas from more than 100 neurons simultaneously. It provides information with single cell resolution about neuronal ensembles dynamics in multiple local circuits.
03:22
Recording Brain Electrical Activity in Behaving Mice Using Multi-Shank Linear Silicon Probes
0 Views •
2025
This video outlines a protocol for implanting a multi-shank linear silicon probe into the mouse brain to measure local field potentials. The procedure involves securing the probe to a stereotaxic unit, positioning it accurately over the target brain region, inserting it into the brain, and securing it with dental cement. After implantation, the assembly is protected with a casing. Following recovery, the setup allows for recording local field potentials, providing insights into neuronal...
09:59
Implantation of Chronic Silicon Probes and Recording of Hippocampal Place Cells in an Enriched Treadmill Apparatus
0 Views •
Cited by 9 •
2017
We describe the diverse steps to implant chronic silicon probes and to record place cells in mice that are running head-fixed on a cue-enriched treadmill apparatus.
08:57
Hybrid Microdrive System with Recoverable Opto-Silicon Probe and Tetrode for Dual-Site High Density Recording in Freely Moving Mice
0 Views •
Cited by 10 •
2019
This protocol describes the construction of a hybrid microdrive array that allows implantation of nine independently adjustable tetrodes and one adjustable opto-silicon probe in two brain regions in freely moving mice. Also demonstrated is a method for safely recovering and reusing the opto-silicon probe for multiple purposes.
FAQs
The multiple recording sites on a silicon probe sample extracellular voltage changes at distributed positions in neural tissue. This lets researchers monitor action potentials and local field potentials at the same time, rather than relying on activity from one location. The resulting measurements support analysis of both individual neuronal activity and broader circuit dynamics.
High-density placement of recording sites gives researchers a spatial view of neural activity rather than measurements tied to a single point. By comparing signals from many locations, they can investigate how activity is organized across circuits and connect those patterns with behavior. This supports studies of sensory processing, movement, learning, and disease.
Recording both action potentials and local field potentials provides complementary views of neural function. Action potential measurements help examine activity at the level of individual neurons, while local field potentials contribute to analysis of larger neural circuits. Their simultaneous collection helps researchers relate cellular activity to circuit-level dynamics within the same experiment.
During Silicon Probe Recording, researchers insert the microfabricated probe into neural tissue and collect extracellular voltage signals from its multiple sites. The distributed measurements allow activity to be monitored at many locations during an investigation. Researchers can then examine neuronal and circuit activity in relation to sensory information, movement, learning, or disease.
Multiple recording sites are the central design feature. Because they are distributed along a microfabricated silicon probe, the instrument can sample neural activity from several locations during one recording. This high-density, spatially distributed arrangement supports detailed examination of circuit dynamics and helps connect electrical activity with behavior.
Researchers can apply this approach when they need to study how neural activity relates to sensory information, guides movement, or changes during learning and disease. Its ability to monitor individual neurons and larger circuits across multiple locations makes it useful for linking cellular signals with circuit dynamics and observed behavior.