Silicone Sheet Assembly

Silicone Sheet Assembly is the process of combining silicone sheets into a defined, functional structure, providing a flexible and durable component for laboratory equipment and experimental setups. Assembly typically involves cutting or shaping sheets, aligning layers, and securing them to create controlled thickness, geometry, or separation between adjacent regions. In neuroscience, these assemblies can support device construction and tissue-handling configurations where compliance, insulation, and resistance to moisture are important. Consistent fabrication improves experimental reproducibility and helps researchers adapt interfaces or chambers to specific preparations, while silicone’s flexibility can reduce mechanical mismatch when components contact delicate biological samples.

Silicone Sheet Assembly - Related Videos

Research

JoVE Journal - Bioengineering

Construction Methods for Hybrid Polycarbonate-Silicon Microfluidic Devices

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2026

This protocol describes three straightforward sealing methods for fabricating a hybrid microfluidic device that integrates polycarbonate and silicon components. By implementing solvent bonding, thermal compression, and mechanical compression strategies, we enable reliable, low-temperature sealing techniques that avoid specialized equipment for hybrid microfluidic devices.

Research

JoVE Journal - Engineering
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Fabrication Process of Silicone-based Dielectric Elastomer Actuators

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Cited by 102 •

2016

This manuscript shows the fabrication process for the manufacture of dielectric elastomer soft actuators based on silicone membranes. The three key stages of production are presented in detail: blade casting of thin silicone membranes; pad printing of compliant electrodes; and the assembly of all the components.

Monolayer Contact Doping of Silicon Surfaces and Nanowires Using Organophosphorus Compounds

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Cited by 9 •

2013

A detailed procedure for surface doping of Silicon interfaces is provided. The ultra-shallow surface doping is demonstrated by using phosphorus containing monolayers and rapid annealing process. The method can be used for doping of macroscopic area surfaces as well as nanostructures.

Construction of Modular Hydrogel Sheets for Micropatterned Macro-scaled 3D Cellular Architecture

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Cited by 4 •

2016

We describe the fabrication of micropatterned hydrogel sheets using a simple process, which can be assembled and manipulated in a freestanding form. Using these modular hydrogel sheets, a simple macro-scaled 3D cell culture system can be generated with a controlled cellular microenvironment.

Research

JoVE Journal - Biology
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Assembly, Loading, and Alignment of an Analytical Ultracentrifuge Sample Cell

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Cited by 21 •

2009

The analytical ultracentrifuge (AUC) sample cell holds sample and reference buffer and during experiments and is exposed to high vacuum and rotor speeds up to 60,000 rpm. This video will demonstrate the rigorous attention to detail necessary for assembly, loading and alignment of this very important component of an AUC experiment.

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