Microfluidic Optomechanical Resonators

Microfluidic optomechanical resonators are miniaturized devices that combine fluid transport, optical resonance, and mechanical vibration to measure physical or chemical changes in tiny liquid volumes. Light confined in an optical cavity interacts with a mechanical mode through radiation pressure; when a sample flows through or surrounds the resonator, changes in refractive index, mass loading, or viscous damping alter the optical spectrum or mechanical response. These coupled signals enable label-free detection and characterization of particles, biomolecules, and fluid properties while using small sample volumes. In physics and lab-on-chip research, the platform supports sensitive sensing, dynamic measurements, and integration with compact analytical systems.

Microfluidic Optomechanical Resonators - Related Videos

Research

JoVE Journal - Engineering

Fabrication and Testing of Microfluidic Optomechanical Oscillators

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Cited by 10 •

2014

Parametric optomechanical excitations have recently been experimentally demonstrated in microfluidic optomechanical resonators by means of optical radiation pressure and stimulated Brillouin scattering. This paper describes the fabrication of these microfluidic resonators along with methodologies for generating and verifying optomechanical oscillations.

Education

JoVE Core - Chemistry

Resonance

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2020

The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds. If nitrite ions do indeed contain a single and a double bond, the two bond lengths are expected to be different. A double bond between two atoms is shorter (and stronger) than a single bond between the same two atoms. However, experiments show that both N–O bonds in NO2− have the same strength and length, and are identical in all other...

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

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Cited by 26 •

2017

Multilayer microfluidic devices often involve the fabrication of master molds with complex geometries for functionality. This article presents a complete protocol for multi-step photolithography with valves and variable height features tunable to any application. As a demonstration, we fabricate a microfluidic droplet generator capable of producing hydrogel beads.

Microfluidic Applications for Disposable Diagnostics

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Cited by 1 •

2008

In this interview, Dr. Klapperich discusses the fabrication of thermoplastic microfluidic devices and their application for development of new diagnostics.

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