Coronary Heart Disease

Coronary heart disease is a condition in which the blood vessels supplying the heart become narrowed or blocked, limiting oxygen delivery to cardiac muscle. It most often develops when atherosclerotic plaques build up in the coronary arteries, reducing blood flow and potentially causing angina, heart attack, or other complications. Psychological factors such as chronic stress, depression, and anxiety can influence cardiovascular risk through physiological stress responses and health behaviors, including smoking, diet, physical activity, and medication adherence. Understanding these interactions supports prevention, behavioral interventions, and comprehensive care that addresses both cardiovascular health and psychological well-being.

Coronary Heart Disease - Related Videos

Research

JoVE Journal - Developmental Biology
Free Sample

Analysis of Coronary Vessels in Cleared Embryonic Hearts

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Cited by 11 •

2016

We present a protocol for the analysis of coronary vessels in whole embryonic murine hearts up to E15.5, using standard immunological staining methods followed by optical clearance and confocal microscopy. This technique enables visualization of blood vessels throughout the entire heart without the need for time-consuming analysis of serial sections.

Research

JoVE Journal - Bioengineering

Procedure for Decellularization of Porcine Heart by Retrograde Coronary Perfusion

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Cited by 68 •

2012

A method to rapidly and completely remove cellular components from an intact porcine heart through retrograde perfusion is described. This method yields a site specific cardiac extracellular matrix scaffold which has the potential for use in multiple clinical applications.

Research

JoVE Journal - Medicine
Free Sample

Implantation of Total Artificial Heart in Congenital Heart Disease

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Cited by 40 •

2014

This is a case report of a patient with congenitally corrected transposition of the great arteries (CCTGA) who received a total artificial heart (TAH) as a bridge to heart transplant. The TAH was successfully implanted with modifications to accommodate the patient's congenitally malformed heart.

Education

JoVE Core - Medical-Surgical Nursing

Coronary Artery Disease II: Pathophysiology

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2025

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...

Coronary Artery Disease I: Introduction

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2025

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...

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