Depression Anxiety Disorders

Depression and anxiety disorders are common mental health conditions marked by persistent low mood or loss of interest, excessive fear or worry, and significant effects on daily functioning. Their development reflects interactions among genetic vulnerability, brain signaling, stress-response systems, psychological processes, and environmental experiences; anxiety can sustain heightened threat responses, while depression can disrupt mood and reward regulation. In psychology, clinicians assess symptom patterns, duration, severity, and co-occurrence to distinguish these disorders and guide care. Evidence-based treatments, including cognitive behavioral therapy, other psychotherapies, and medication, can reduce symptoms, improve functioning, and support research into personalized prevention and intervention.

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Education

JoVE Core - Introduction to Psychology

Generalized Anxiety Disorder

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2025

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...

Social Anxiety Disorder

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2025

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.

Depressive Disorders: Etiology

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2025

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression. Biological Factors in Depression Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Anxiety Testing

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2023

Anxiety is a commonly observed behavioral disorder that stems from fear. It is described as increased restlessness, or unpleasant feelings of fear over anticipated events. Experimenters often use rodent models to better understand anxiety disorders in humans. They use different paradigms, like exposing rodents to bright spaces or loud sounds, which are known to induce fear. These tests combined with other interventions such as surgery or drug-administration may assist researchers in pinpointing...

Research

JoVE Journal - Behavior
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Reducing State Anxiety Using Working Memory Maintenance

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Cited by 7 •

2017

This protocol demonstrates how to measure anxiety-potentiated startle during the Sternberg Working Memory paradigm.

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