Tail Sensitivity Analysis

Tail sensitivity analysis is a statistical approach for assessing how conclusions change when assumptions about the extreme ends, or tails, of a probability distribution are altered. It typically varies the distributional model, tail heaviness, cutoff threshold, or dependence structure, then compares resulting estimates of rare-event probabilities, extreme quantiles, or risk measures. This analysis reveals whether findings are robust to plausible changes in tail behavior and helps identify when standard models may understate or overstate extreme outcomes. It supports more reliable decision-making in fields such as finance, environmental science, engineering, and public health, where low-probability events can have substantial consequences.

Tail Sensitivity Analysis - Related Videos

Research

JoVE Journal - Neuroscience

The Tail Suspension Test

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Cited by 534 •

2012

The tail-suspension test is validated as an experimental procedure to assess antidepressant efficacy of drug treatments in mice. Mice are suspended by their tails for six minutes and escape-related behaviors are assessed. We describe procedures used in conducting the tail suspension test.

Paw-Dragging: a Novel, Sensitive Analysis of the Mouse Cylinder Test

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Cited by 53 •

2015

Classical forelimb asymmetry analysis of the cylinder test is routinely used to assess behavioural deficits in rats following brain injury or stroke; however, it fails to detect consistent deficits in mice. This study demonstrates that quantifying paw-dragging behaviour is a more sensitive analysis of brain injury in mice.

Education

JoVE Business - Accounting

Using Sensitivity Analysis to Optimize Profits

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2026

Sensitivity analysis is a vital tool in managerial decision-making, particularly when evaluating how changes in key business variables such as costs, prices, or sales volumes affect overall profitability. This technique provides managers with a systematic approach to assess the financial implications of alternative strategies and external uncertainties.Sensitivity analysis involves altering one or more variables in a financial model to measure the impact on key outcomes, such as net income or...

Murine Tail Lymphedema Model: An In Vivo Technique to Generate Sustained Lymphedema in Murine Tail

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2025

This video describes an in vivo technique to generate murine tail lymphedema, an abnormal fluid accumulation in the interstitial tissue space leading to swelling in the tail. The model is applied to study mechanisms and therapy for lymphedema.

Isolation of Genomic DNA from Mouse Tails

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Cited by 23 •

2007

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