Hippocampus Dependent Task

A hippocampus-dependent task is a behavioral test that measures learning or memory processes requiring the hippocampus, a brain region central to forming relational, spatial, and contextual representations. Performance typically depends on encoding relationships among events, locations, or environmental cues and consolidating those representations so they can be retrieved later; disruptions to hippocampal function therefore impair task-specific memory while often sparing simpler sensory or motor responses. Researchers use these tasks in rodents and other models to assess memory, investigate neural circuits and plasticity, and evaluate how aging, neurological disease, stress, or experimental treatments affect cognition.

Hippocampus Dependent Task - Related Videos

Education

JoVE Science Education - Psychology

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2023

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California Our experience of memory is varied and complex. Sometimes we remember events in vivid detail, while other times we may only have a vague sense of familiarity. Memory researchers have made a distinction between memories that are recollected versus those that are familiar. A recollected item is one that is not only remembered, but carries with it details of the time at which it was learned or encoded.

Piaget's Conservation Task and the Influence of Task Demands

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2023

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Marginal Dishonesty: The Adding-to-10 Task

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2023

Source: Julian Wills & Jay Van Bavel—New York University Classical economic theory asserts that people are rational and self-interested. In addition to seeking wealth and status, people are motivated by other goals. As a result, financial motives can sometimes be dwarfed by other internal needs, such as maintaining a positive self-concept or affiliating with other group members. Ethical dilemmas, such as the temptation to cheat on taxes, can result when these motives are in conflict. On...

Research

JoVE EoE - Neurophysiology

In Vitro Recording of Theta Oscillations in the Mouse Hippocampus

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2025

This video demonstrates the recording of rhythmic neuronal network activity, also known as theta oscillations, in an isolated hippocampus. Electrodes are inserted into various layers and spatial positions to detect and analyze theta oscillations. This shows the unique neuronal compositions and the connectivity of the neuronal network across different layers of the hippocampus.

Decision-making and the Iowa Gambling Task

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2023

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California Decision-making is an important component of human executive function, in which a choice about a course of action or cognition is made from many possibilities. Damage to the inferior parts of the frontal lobes can affect a person's ability to make good decisions. However, while decision-making deficits can have a large impact on one's life, these deficits can be difficult to quantify in the laboratory.

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