Fluidic Device
Fluidic Device - Related Videos
12:32
Combining Fluidic Devices with Microscopy and Flow Cytometry to Study Microbial Transport in Porous Media Across Spatial Scales
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Cited by 2 •
2020
Breakthrough curves (BTCs) are efficient tools to study the transport of bacteria in porous media. Here we introduce tools based on fluidic devices in combination with microscopy and flow cytometric counting to obtain BTCs.
13:36
Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits
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Cited by 10 •
2010
Controlling and analyzing neural circuits in vivo would be facilitated by a technology for delivery of viruses and other reagents to desired 3-dimensional sets of brain regions. We demonstrate customized fluidic injector array fabrication, and delivery of virally-encoded optical sensitizers, enabling optical manipulation of complex brain circuits.
08:29
Thermal Measurement Techniques in Analytical Microfluidic Devices
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Cited by 6 •
2015
Here, we present three protocols for thermal measurements in microfluidic devices.
08:18
Construction Methods for Hybrid Polycarbonate-Silicon Microfluidic Devices
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2026
This protocol describes three straightforward sealing methods for fabricating a hybrid microfluidic device that integrates polycarbonate and silicon components. By implementing solvent bonding, thermal compression, and mechanical compression strategies, we enable reliable, low-temperature sealing techniques that avoid specialized equipment for hybrid microfluidic devices.
10:22
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
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Cited by 1 •
2009
A novel microfluidic system has been developed using the phenomenon of passive pumping and a user controlled fluid delivery system. This microfluidic system has the potential to be used in a wide variety of biological applications given its low cost, ease of use, volumetric precision, high speed, repeatability and automation.
FAQs
Pressure differences create the driving force that moves liquids or gases through connected channels. Pumps can generate or maintain this force, while valves regulate when and where flow proceeds. Together, these components allow researchers to direct samples, coordinate delivery, and establish controlled operating conditions for assays or other bioengineering experiments.
Channel geometry determines how fluids are guided and influences processes such as mixing, separation, and delivery. At small scales, surface forces can also help direct fluids without relying solely on external pumping. Adjusting these features gives researchers spatial control over fluid behavior and supports precise manipulation of limited biological samples.
The device can alter flow paths, channel dimensions, pressure conditions, or valve states to control how fluids meet and move. These physical controls regulate contact between streams and the progression of separation steps. Such control helps produce repeatable handling conditions while preserving the sample for downstream analysis or biological use.
A basic workflow begins by introducing the relevant liquid or gas into designed channels, then applying pressure, pumping, valve control, geometry, or surface forces to guide it. Researchers can direct delivery, promote mixing, or perform separation before collecting the resulting output. The specific sequence depends on whether the goal is an assay, cell handling, or analysis.
Researchers may choose this approach when an assay requires precise control of small sample volumes, flow paths, or timing. The device can support controlled transport and mixing while improving experimental efficiency. This is especially useful for bioengineering assays involving biomolecule analysis or other measurements that benefit from spatial and temporal regulation.
In cell handling, these systems provide controlled transport and positioning of cells. For tissue models, they help reproduce aspects of complex biological environments through regulated fluid movement. In drug delivery, they support controlled delivery conditions. These uses connect fluid management with biological organization, exposure, and experimental reproducibility in bioengineering research.
Fluidic devices can contribute to portable diagnostic platforms by integrating controlled transport, mixing, separation, and analysis in a compact system. Their ability to manipulate small sample volumes can improve experimental efficiency and reduce handling demands. This makes them relevant when researchers need spatially controlled assays that can support more portable testing formats.