Interventional Mri Guidance
Interventional Mri Guidance - Related Videos
08:20
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
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Cited by 31 •
2015
Here we outline the procedure for MRI-guided repetitive transcranial magnetic stimulation to the dorsomedial prefrontal cortex as an experimental treatment for major depressive disorder.
06:06
Optogenetic Functional MRI
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Cited by 15 •
2016
This protocol describes the steps and data analysis required to successfully perform optogenetic functional magnetic resonance imaging (ofMRI). ofMRI is a novel technique that combines high-field fMRI readout with optogenetic stimulation, allowing for cell type-specific mapping of functional neural circuits and their dynamics across the whole living brain.
10:14
Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
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Cited by 9 •
2016
This protocol describes a bioprinting methodology using an automated robotic depositing system that incorporates etched topographical guidance cues with the precision deposition of a cell bearing hydrogel bioink. The printed cells are directly delivered to the etched features and are able to sense and orientate with them.
03:59
MRI-Guided Repetitive Transcranial Magnetic Stimulation to the Dorsomedial Prefrontal Cortex
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2025
Source: Dunlop, K., et al. MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder. J. Vis. Exp. (2015)This video demonstrates the procedure for MRI-guided repetitive transcranial magnetic stimulation (rTMS) targeting the dorsomedial prefrontal cortex (dmPFC) to treat depression.
01:34
Early Intervention and Pain Management
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2026
All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Monitoring Animals for Signs of Pain and Distress Recognizing early signs of pain is essential for ethical animal research. Animals are routinely monitored using behavioral, physical, and physiological parameters that reflect...
FAQs
Rapid image updates provide continuing information about anatomy, target movement, and device position as the procedure progresses. This allows clinicians to recognize changes rather than relying only on an initial plan. They can then adjust a device trajectory or modify treatment delivery in response to the observed conditions, supporting more precise procedural control.
Detailed soft-tissue visualization helps distinguish the intended target and surrounding anatomy during minimally invasive work. Because MRI does not use ionizing radiation, it can provide this imaging information while the intervention is being performed without introducing that type of exposure. Together, these characteristics support image-guided procedures that require anatomical detail and ongoing assessment.
Bioengineering contributes several coordinated elements: MRI-compatible instruments, robotic systems, imaging sequences, and therapeutic platforms. These components must support the imaging environment while allowing clinicians to navigate, monitor, or deliver treatment. Their integration makes it possible to connect anatomical visualization with device positioning and therapy delivery, creating a technical foundation for targeted interventions.
The method links updated images with procedural decision-making. When imaging shows that anatomy or a target has moved, or that a device is no longer positioned as intended, clinicians can revise the trajectory or treatment delivery. This feedback process helps maintain alignment between the planned intervention and the changing conditions observed during the procedure.
A procedure can use MRI guidance across four connected stages: planning the intervention, navigating toward the target, monitoring progress, and assessing the result. Imaging contributes different information at each stage, from anatomical preparation to device-position checks and treatment evaluation. This sequence supports minimally invasive work that may require adjustments during execution rather than only afterward.
Interventional MRI guidance can support biopsy, ablation, drug delivery, and other targeted interventions. During these procedures, imaging can show the relevant soft tissue, target movement, and device position, while later assessment can help evaluate treatment effects. The resulting information supports procedural precision, control of delivery or trajectory, and review of the intervention outcome.