Led Irradiation

LED irradiation is a method that exposes biological materials, cells, tissues, or organisms to controlled light emitted by light-emitting diodes, enabling precise study or modulation of light-dependent responses. Its effects depend on wavelength, irradiance, exposure time, and distance, because cellular or molecular chromophores absorb selected photons and convert that energy into chemical or physiological signals; in photosynthetic systems, light can also drive photochemical reactions. In biology, researchers use LED irradiation to regulate cell behavior, investigate photobiology, support photosynthesis experiments, and evaluate light-based approaches such as photobiomodulation or microbial inactivation. Tunable, energy-efficient LEDs improve reproducibility and enable wavelength-specific experimental designs.

Led Irradiation - Related Videos

Research

JoVE Journal - Neuroscience

Using Affordable LED Arrays for Photo-Stimulation of Neurons

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Cited by 7 •

2011

Adult-born neurons expressing ChR2 can be manipulated in slice electrophysiological preparations in order to examine their contribution towards the function of olfactory neural circuits.

A Mouse Model of Fatigue Induced by Peripheral Irradiation

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Cited by 18 •

2017

We describe a method using targeted peripheral irradiation to induce fatigue-like behavior in mice. The selected non-lethal irradiation dose leads to a week-long reduction in voluntary wheel-running activity.

Planarian Immobilization, Partial Irradiation, and Tissue Transplantation

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Cited by 20 •

2012

An effective method for grafting tissue of defined and consistent size between planaria is described. Also included is a description of how the immobilization technique used for transplantation can be adapted, in conjunction with lead shields, for the partial irradiation of live animals.

UV Irradiation: A Method to Integrate Extrachromosomal Arrays

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2023

Microinjection of transgenes usually results in C. elegans strains with large extrachromosomal arrays, which result in variable expression and transmission of the transgene. UV Irradiation can induce chromosomal integration of the array and more stable transgene transmission.

Investigation of a Blue Light LED Device to Suppress Wound Pathogens Using a Collagen-Based Synthetic Skin Model

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2026

A 405 nm blue light LED device demonstrates antimicrobial efficacy against a broad range of wound pathogens when evaluated on a collagen-based synthetic skin model. This simplified in vitro approach offers a reproducible and ethically viable alternative for early-phase evaluation of light-based antimicrobial therapies.

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