Reservoir Systems

Reservoir systems are biological, environmental, or artificial settings that maintain a substance, organism, or infectious agent and allow it to persist over time. In clinical and infectious disease research, a reservoir supports pathogen survival through colonization, replication, or protected persistence, followed by shedding or release that enables transmission to susceptible hosts. Identifying reservoirs helps researchers trace infection sources, explain recurrence, and distinguish ongoing transmission from reactivation. Clinical applications include infection surveillance, outbreak investigation, antimicrobial and vaccination strategies, and the design of interventions that interrupt pathogen maintenance or movement between hosts, healthcare environments, and broader ecosystems.

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Education

JoVE Core - Microbiology

Reservoir of Infection

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2026

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

Veins as Blood Reservoirs

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2024

Veins, while chiefly responsible for circulating blood back to the heart, also function as storage vessels for blood. They house approximately 64 percent of the body's total blood volume, a feat made possible by their high capacitance—the inherent ability to expand and accommodate large volumes of blood, even under low pressure. The large diameter and thin walls of veins augment their distensibility, significantly more so than arteries, due to their classification as capacitance vessels. When...

Research

JoVE Journal - Engineering
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Reservoir Condition Pore-scale Imaging of Multiple Fluid Phases Using X-ray Microtomography

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Cited by 28 •

2015

We present a methodology for the imaging of multiple fluid phases at reservoir conditions by the use of x-ray microtomography. We show some representative results of capillary trapping in a carbonate rock sample.

The Use of Chemostats in Microbial Systems Biology

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Cited by 67 •

2013

Cell growth rate is a regulated process and a primary determinant of cell physiology. Continuous culturing using chemostats enables extrinsic control of cell growth rate by nutrient limitation facilitating the study of molecular networks that control cell growth and how those networks evolve to optimize cell growth.

Research

JoVE Journal - Environment
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Measurement of the Rheology of Crude Oil in Equilibrium with CO2 at Reservoir Conditions

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Cited by 2 •

2017

A method for measuring the rheology of crude oil in equilibrium with carbon dioxide at reservoir conditions is presented.

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