Newborn Piglet

A newborn piglet is a pig during the immediate postnatal period, when rapid physiological adaptation makes it an important subject in veterinary and biomedical medicine. After birth, the piglet must establish breathing and circulation, maintain body temperature, and obtain energy and passive immunity by nursing colostrum, whose immunoglobulins are absorbed through the immature intestine soon after delivery. Assessing suckling, hydration, temperature, weight gain, and behavior helps identify weakness, hypothermia, starvation, or infection. Newborn piglets therefore support neonatal clinical care, studies of early-life disease and nutrition, and biomedical research requiring an animal model of developing physiology.

Newborn Piglet - Related Videos

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JoVE Journal - Medicine
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Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

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2025

This protocol describes the development of a neonatal piglet model of acute lung injury that models early pathogenic events occurring in the preterm lung, including sub-adequate surfactant quantity, hyperoxia, high-pressure ventilation, and inflammation, to facilitate understanding of molecular triggers of bronchopulmonary dysplasia and enhance therapeutic translation.

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JoVE Journal - Medicine

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

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Cited by 37 •

2015

Hypoxic-ischemic encephalopathy following perinatal asphyxia can be studied using animal models. We demonstrate the procedures necessary for establishing a piglet model of neonatal hypoxic-ischemic encephalopathy.

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

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Cited by 22 •

2015

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.

Recording Brain Signals from Freely Moving Piglets

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2025

This video demonstrates the recording of brain signals from a freely moving piglet. The piglet's head is cleaned, and the electrodes are attached. These electrodes are then connected to a telemetry unit. The setup is secured with silicone rubber. The piglet is allowed to acclimate before data recording.

Research

JoVE Journal - Medicine
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Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity (AIDN): A Translational Neuroscience Approach

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Cited by 11 •

2017

Anesthesia-induced developmental neurotoxicity (AIDN) research has focused on rodents, which are not broadly applicable to humans. Non-human primate models are more relevant, but are cost-prohibitive and difficult to use for experimentation. The piglet, in contrast, is a clinically relevant, practical animal model ideal for the study of anesthetic neurotoxicity.

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