Septal Coronary Aortic Banding
Septal Coronary Aortic Banding - Related Videos
06:39
Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
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Cited by 20 •
2015
Coronary flow reserve (CFR) is useful for assessment of myocardial oxygen demand and evaluation of cardiovascular risk. This study establishes a step-by-step transthoracic Doppler echocardiographic (TTDE) method for longitudinal monitoring of the changes in CFR, as measured from coronary artery in mice, under the experimental pressure overload of aortic banding.
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Cited by 4 •
2017
Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.
04:38
Transverse Aortic Arch Banding in Mouse Model: A Minimally Invasive Technique in Mice for Induction of High Pressure in the Left Ventricle
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2025
In this video, we demonstrate an experimental protocol for minimally invasive transverse aortic constriction in mice to examine pressure overload-induced heart failure.
09:24
O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy
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Cited by 1 •
2022
The present protocol describes a new technique of aortic banding in mice to induce pressure overload cardiac hypertrophy. For banding, a rubber ring with a fixed inner diameter is used. This new technique promises less variance and more reproducible data for future experiments.
02:35
Band Theory
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2020
When two or more atoms come together to form a molecule, their atomic orbitals combine and molecular orbitals of distinct energies result. In a solid, there are a large number of atoms, and therefore a large number of atomic orbitals that may be combined into molecular orbitals. These groups of molecular orbitals are so closely placed together to form continuous regions of energies, known as the bands. The energy difference between these bands is known as the band gap. Conductor, Semiconductor,...
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The band reduces the vessel’s lumen and increases resistance, changing both pressure loading and coronary blood flow. The ventricle must respond to altered hemodynamic demands while the septal coronary circulation receives modified perfusion. Together, these effects create a controlled stress environment in which investigators can examine how myocardial tissue adapts to increased workload or reduced coronary supply.
Calibration determines the degree of vascular narrowing and therefore influences the magnitude of resistance, pressure load, and perfusion change. Consistent calibration helps produce comparable cardiac responses among experimental subjects. It also allows researchers to relate the severity of the imposed hemodynamic disturbance to remodeling outcomes such as ventricular hypertrophy or functional impairment.
This model supports analysis of myocardial adaptation to pressure overload and coronary insufficiency. Investigators can follow how altered loading and perfusion contribute to ventricular hypertrophy, declining cardiac function, and progression toward heart failure. Because the hemodynamic disturbance is experimentally controlled, the model helps connect vascular changes with later structural and functional consequences.
The procedure requires placing a calibrated band around the selected vascular structure associated with the aorta and septal coronary circulation. The band is positioned to narrow the lumen and create the intended resistance. Successful model establishment depends on controlled placement and calibration, because inconsistent narrowing can produce variable pressure, perfusion, and remodeling responses.
Researchers may choose this approach when they need a reproducible combination of altered coronary perfusion and increased ventricular workload. It is particularly relevant for studies of coronary insufficiency, pressure overload, and heart failure. The model can also provide a structured setting for testing interventions intended to limit remodeling or preserve cardiac function under these stresses.
Investigators can assess structural remodeling, including ventricular hypertrophy, alongside functional impairment and progression toward heart failure. These outcomes show how the myocardium responds over time to altered pressure and coronary supply. The model also supports comparison of therapeutic interventions, helping determine whether a treatment reduces adverse remodeling or maintains cardiac performance despite the imposed vascular change.