Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Alice Sosic; Marta Cappellini; Matteo Scalabrin; Barbara Gatto

doi:10.3791/52474

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İmmünoloji ve Enfeksiyon

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Nucleocapsid Tavlama Dolayımlı Elektroforez (ADI) Testi HIV-1 Nükieokapsit inhibitörlerinin Hızlı tanımlanması sağlar

Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

JoVE Journal
İmmünoloji ve Enfeksiyon

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JoVE Journal İmmünoloji ve Enfeksiyon

Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Nucleocapsid Tavlama Dolayımlı Elektroforez (ADI) Testi HIV-1 Nükieokapsit inhibitörlerinin Hızlı tanımlanması sağlar

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8,855 Views

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08:33 min

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January 19, 2015

DOI:

10.3791/52474-v

DOI:

10.3791/52474-v

•

08:33 min

January 19, 2015

•

2 Views

Alice Sosic¹, Marta Cappellini¹, Matteo Scalabrin², Barbara Gatto¹

¹Department of Pharmaceutical and Pharmacological Sciences,University of Padova, ²The RNA Institute,SUNY Albany

Özet

This protocol describes NAME, an assay that allows the rapid identification of molecules able to inhibit in vitro the chaperone activities of HIV-1 nucleocapsid protein.

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Nucleocapsid Tavlama Dolayımlı Elektroforez (ADI) Testi HIV-1 Nükieokapsit inhibitörlerinin Hızlı tanımlanması sağlar

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