Apolipoprotein E-eksik farelerde Mineralocorticoid reseptörlerinin etkinleştirmesi üzerinden aterosklerotik plaklar indüksiyon
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September 26, 2018
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Özet
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ApoE- / - fareler aldosteron sürekli bir sürüm boyunca aterojenik bir diyet ile beslenen aort kökünde ateroskleroz ikna etmek için bir protokol açıklar. Plak kompozisyon karakterize yöntemleri de açıklanmaktadır.
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Marzolla, V., Armani, A., Mammi, C., Feraco, A., Caprio, M. Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice. J. Vis. Exp. (139), e58303, doi:10.3791/58303 (2018).
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