Low-stress Route Learning Using the Lashley III Maze in Mice

Amanda Bressler; David Blizard; Anne Andrews

doi:10.3791/1786

Journal

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Neuroscience

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Low-stress Route Learning Using the Lashley III Maze in Mice

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Low-stress Route Learning Using the Lashley III Maze in Mice

17,778 Views

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09:14 min

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May 22, 2010

DOI:

10.3791/1786-v

DOI:

10.3791/1786-v

•

09:14 min

May 22, 2010

•

10 Views

Amanda Bressler¹, David Blizard², Anne Andrews^3,4,5,6

¹Department of Chemistry,Pennsylvania State University, ²Center for Developmental and Health Genetics,Pennsylvania State University, ³Department of Veterinary and Biomedical Sciences,Pennsylvania State University, ⁴Huck Institute of the Life Sciences,Pennsylvania State University, ⁵California NanoSystems Institute,University of California, Los Angeles, ⁶Semel Institute of Neuroscience and Human Behavior,University of California, Los Angeles

Summary

The Lashley III maze is a route-learning task that does not rely on aversive stimuli or visual cues. It is thus a highly attractive option for evaluating learning and memory, especially in aging mice or otherwise where stress is a consideration.

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Low-stress Route Learning Lashley III Maze Mice Behavior Tests Learning And Memory Visual Cues Aversive Stimuli Sensory Modalities Aging Animals Confounding Effects Maze Navigation Low Stress Conditions Dark Phase Food/water Deprivation Pseudo-home Cage

Low-stress Route Learning Using the Lashley III Maze in Mice

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Summary

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