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JoVE Journal
Neuroscience

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Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology
 

Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology

Article DOI: 10.3791/2032
November 6th, 2010

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Summary November 6th, 2010

We provide a reproducible method for culturing confluent monolayers of human fetal retinal pigment epithelial cells (hfRPE) cells that exhibit morphology, physiology, polarity, and protein and gene expression patterns of adult native tissue. This work has been extended to an animal model of several eye diseases.

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