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JoVE Journal
Neuroscience

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Mechanical Manipulation of Neurons to Control Axonal Development
 

Mechanical Manipulation of Neurons to Control Axonal Development

Article DOI: 10.3791/2509
April 10th, 2011

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Summary April 10th, 2011

Application and direct measurements of forces on neurons in the 2-1000 microdyne range are achieved with high precision using calibrated glass needles. This methodology can be used to control and measure several aspects of axonal development, including axonal initiation, axonal tension, velocity of axonal elongation, and force vectors.

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