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JoVE Journal
Medicine

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Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice
 

Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice

Article DOI: 10.3791/2525
May 5th, 2011

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Summary May 5th, 2011

A murine model for ventilator induced lung injury is an important tool to study an acute lung injury in vivo. Here, we report an easy applicable in situ model for acute lung injury using high-pressure mechanical ventilation to induce acute failure of the lung.

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