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JoVE Journal
Neuroscience

This content is Open Access.

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model
 

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Article doi: 10.3791/2831
July 26th, 2011

Summary July 26th, 2011

One of the pathological characteristics of AD is the formation of Amyloid β protein positive neuritic plaques. In this protocol we describe two methods to detect neuritic plaques in transgenic AD model mice: immunohistochemical detection using the ABC and DAB method and fluorescent detection using thioflavin S staining method.

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