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Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures
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Chapters
- 00:05Title
- 02:09Preparation of a Glass Chamber with Integrated Microelectrode Arrays (MEA)
- 05:00Cortex and Ventral Tegmental Area (VTA) Tissue Dissection
- 08:46Mounting Cortex and VTA Tissue Slices on the MEA
- 11:20Electrophysiological Recording of Spontaneous and Stimulus-Evoked Neural Activity
- 13:38MEA Recording Results
- 15:31Conclusion
A robust way to study neuronal avalanches, i.e. scale-invariant spatio-temporal activity bursts, indicative of critical state dynamics in cortex. Avalanches emerge spontaneously in developing superficial layers of cultured cortex which allows for long-term measurements of the activity with planar integrated multi-electrode arrays (MEA) under precisely controlled conditions.
Tags
Multi-electrode Array RecordingsNeuronal AvalanchesOrganotypic CulturesCortex ActivityOngoing ActivitySpontaneous ActivityMigration Of Cortex Cell TypesFormation Of Neuronal ConnectionsSensory Stimuli IntegrationCortex FunctionRecording TechniquesLocal Field Potential (LFP)Extracellular MicroelectrodesElectroencephalogram (EEG)Magnetoencephalogram (MEG)BOLD SignalFunctional Magnetic Resonance Imaging (fMRI)Mesoscopic ScaleSynchronized ActivitiesDeflections In LFPArray Of Microelectrodes
