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T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

DOI:
10.3791/3300-v

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17:45 min

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February 26, 2012

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, , , ,
1Division of Systems Medical Science, Institute for Comprehensive Medical Science,Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences,National Institutes of Natural Sciences

Chapters

  • 00:02Title
  • 00:06Apparatus Set Up
  • 02:52Animal Preparation and Food Deprivation
  • 04:47Pre-training
  • 05:46Forced Alternation Task
  • 12:06Left-Right Discrimination Task
  • 14:08Representative Results
  • 14:48Conclusion

Summary

Automatic Translation

Automatic Translation

This article presents the protocol of T-maze tests using a modified automated apparatus for assessing the learning and memory functions in mice.

Tags

T-mazeForced Alternation TaskLeft-right Discrimination TaskWorking MemoryReference MemoryGenetically Engineered MiceAutomated ApparatusVideo-tracking SystemModified T-maze ApparatusStart BoxT-shaped AlleyPellet DispensersL-shaped AlleysMicrodialysisElectrophysiologyOptogenetics Techniquesα-CaMKII+/- Mice

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