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JoVE Journal
Bioengineering

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Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening
 

Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening

Article DOI: 10.3791/3845
July 18th, 2012

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Summary July 18th, 2012

We have developed a high-density microarray platform consisting of 3D nano-biofilms of C. albicans called CaBChip. The susceptibility profile of drugs tested on a CaBChip is comparable to the conventional 96-well plate model, suggesting that the fungal chip is ideally suited for true high-throughput screening of antifungal drugs.

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