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Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
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Bioengineering
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JoVE Journal Bioengineering
Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries

DOI:
10.3791/3882-v

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10:58 min

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September 06, 2012

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, ,
1Department of Chemical and Biological Engineering,Iowa State University

Chapters

  • 00:05Title
  • 02:06Combinatorial Polymer Library Synthesis
  • 05:03Combinatorial Blank- and Protein-loaded Polymer Nanoparticle Fabrication
  • 06:53High-throughput Protein Release Kinetics
  • 08:54Release Kinetics Results of Protein-encapsulated Polymer Libraries
  • 10:18Conclusion

Summary

Automatic Translation

Automatic Translation

This method describes the combinatorial synthesis of biodegradable polyanhydride film and nanoparticle libraries and the high-throughput detection of protein release from these libraries.

Tags

Combinatorial SynthesisHigh-throughputProtein ReleasePolymer FilmNanoparticle LibrariesPolyanhydridesBiomaterialsDrug DeliveryOptimizationDesign ProcessVaccine DeliveryBiodegradableDetection Of Protein ReleaseRobotically Operated MethodLabVIEWHands-free Automated ProtocolMicro-scale Polymer LibrariesMultivariant Polymer Systems

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