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JoVE Journal
Biology

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Generation of Mice Derived from Induced Pluripotent Stem Cells
 

Generation of Mice Derived from Induced Pluripotent Stem Cells

Article DOI: 10.3791/4003
November 29th, 2012

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Summary November 29th, 2012

Generating induced pluripotent stem cell (iPSC) lines produces lines of differing developmental potential even when they pass standard tests for pluripotency. Here we describe a protocol to produce mice derived entirely from iPSCs, which defines the iPSC lines as possessing full pluripotency1.

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