3.27
A seizure is a transient episode of abnormal, excessive electrical activity in the brain that disrupts normal neurologic function. Epilepsy is a disorder in which a person has a long-term tendency to have repeated, unprovoked seizures.
Some seizures cause convulsions—violent shaking due to rapid muscle contractions. Others may be more subtle but less easily recognized.
Focal seizures begin in a specific region of the brain and may or may not impair awareness. When awareness is preserved, sensory symptoms such as tingling or unusual smells are referred to clinically as an aura.
Generalized seizures affect both sides of the brain at once. A person may collapse, stiffen, and jerk rhythmically.
A prodrome may appear hours earlier with nonspecific symptoms, like mood changes or headaches. The postictal state is a temporary period following a seizure, often marked by confusion or fatigue.
Status epilepticus is a life-threatening emergency defined as a seizure lasting more than five minutes or repeated seizures without regaining consciousness between episodes.
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.
Definitions
A seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures, reflecting an underlying tendency of the brain to generate abnormal electrical activity due to genetic, structural, or metabolic causes. A convulsion is a seizure characterized by intense, involuntary muscle contractions; not all seizures are convulsive, such as absence seizures.
Classification of Seizures
Seizures are classified as provoked or unprovoked. Provoked seizures occur due to identifiable causes like trauma, infection, or metabolic disturbances, while unprovoked seizures are not linked to immediate triggers and are often associated with epilepsy. Focal seizures originate in a specific brain region and may occur with preserved awareness (causing unusual sensations) or impaired awareness (leading to staring or repetitive movements). Generalized seizures involve both hemispheres from onset and always impair consciousness, including tonic-clonic, absence, myoclonic, atonic, tonic, and clonic types.
Additional Key Terms
Other important terms include epileptic spasms, seen mainly in infants as sudden body movements in clusters; aura, a warning sensation before some focal seizures; postictal state, the recovery phase marked by confusion or drowsiness; and status epilepticus, a medical emergency involving prolonged or repeated seizures without recovery.
A seizure is a transient episode of abnormal, excessive electrical activity in the brain that disrupts normal neurologic function. Epilepsy is a disorder in which a person has a long-term tendency to have repeated, unprovoked seizures.
Some seizures cause convulsions—violent shaking due to rapid muscle contractions. Others may be more subtle but less easily recognized.
Focal seizures begin in a specific region of the brain and may or may not impair awareness. When awareness is preserved, sensory symptoms such as tingling or unusual smells are referred to clinically as an aura.
Generalized seizures affect both sides of the brain at once. A person may collapse, stiffen, and jerk rhythmically.
A prodrome may appear hours earlier with nonspecific symptoms, like mood changes or headaches. The postictal state is a temporary period following a seizure, often marked by confusion or fatigue.
Status epilepticus is a life-threatening emergency defined as a seizure lasting more than five minutes or repeated seizures without regaining consciousness between episodes.
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