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在黑质和腹侧被盖区多巴胺调控的综合性能分析
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Neuroscience
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JoVE Journal Neuroscience
Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
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在黑质和腹侧被盖区多巴胺调控的综合性能分析

DOI:
10.3791/4171-v

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09:54 min

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August 10, 2012

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, , ,
1Department of Pharmacology, Toxicology, & Neuroscience,Louisiana State University Health Sciences Center

Chapters

  • 00:05Title
  • 02:38Dissection
  • 04:51Tissue Analysis: Total Protein and Final Normalization of Tyrosine Hydroxylase and Dopamine Active Transporter Results
  • 08:12Results: Tyrosine Hydroxylase Phosphorylation in Rat Substantia Nigra and Ventral Tegmental Samples
  • 09:00Conclusion

Summary

Automatic Translation

Automatic Translation

多巴胺是明显的调节中脑核，其中包含的多巴胺神经元的胞体和树突。在这里，我们描述了一次解剖和样品处理方法效果发挥到极致，因此，结论和见解，在黑质（SN）和腹侧被盖区（VTA）在啮齿动物的脑核的多巴胺调节。

Tags

Dopamine RegulationNeurotransmitterCNSLocomotor ActivityReward-related BehaviorMolecular DeficienciesNigrostriatal PathwayMesoaccumbens PathwayStriatumNucleus AccumbensTyrosine Hydroxylase ProteinTH PhosphorylationDopamine Transporter ProteinVesicular Monoamine Transporter 2 ProteinPost-translational ModificationsMidbrain

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