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Neuroscience

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JoVE Journal Neuroscience
Simultaneous Intracellular Recording of a Lumbar Motoneuron and the Force Produced by its Motor Unit in the Adult Mouse In vivo
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Journal (Neuroscience)
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Simultaneous Intracellular Recording of a Lumbar Motoneuron and the Force Produced by its Motor Unit in the Adult Mouse In vivo

Article DOI: 10.3791/4312
December 5th, 2012 •
1, 1
1Department of Physiology, Northwestern University Feinberg School of Medicine

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December 5th, 2012

This new method permits the simultaneous intracellular recording of a single adult mouse motoneuron and the measurement of the force produced by its muscle fibers. The combined investigation of the electrical and mechanical properties of motor units in normal and genetically modified animals is a breakthrough for the study of the neuromuscular system.

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