A non-invasive means to evaluate the success of myoblast transplantation is described. The method takes advantage of a unified fusion reporter gene composed of genes whose expression can be imaged with different imaging modalities. Here, we make use of a fluc reporter gene sequence to target cells via bioluminescence imaging.
Gutpell, K., McGirr, R., Hoffman, L. Molecular Imaging to Target Transplanted Muscle Progenitor Cells. J. Vis. Exp. (73), e50119, doi:10.3791/50119 (2013).