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In Vivo Two-photon Imaging Of Experience-dependent Molecular Changes In Cortical Neurons
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1Unit on Neural Circuits and Adaptive Behaviors, Genes Cognition and Psychosis Program,National Institute of Mental Health, 2Department of Neuroscience,Brown University – National Institutes of Health Graduate Partnership Program, 3Section on Synaptic Pharmacology, Laboratory for Integrative Neuroscience,National Institute on Alcohol Abuse and Alcoholism, 4Champalimaud Neuroscience Programme,Champalimaud Center for the Unknown
Chapters
- 00:00Title
- 01:37Pre-operative Preparation
- 02:42Cranial Window Surgery
- 05:40Behavior and Two-photon Imaging
- 08:29Conclusion
Experience-dependent molecular changes in neurons are essential for the brain's ability to adapt in response to behavioral challenges. An in vivo two-photon imaging method is described here that allows the tracking of such molecular changes in individual cortical neurons through genetically encoded reporters.
