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Stereotaktisk Injektion af MicroRNA-udtrykkende lentivira til Mouse Hippocampus CA1 Region og vurdering af de Behavioral Outcome
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Stereotaktisk Injektion af MicroRNA-udtrykkende lentivira til Mouse Hippocampus CA1 Region og vurdering af de Behavioral Outcome

Article DOI: 10.3791/50170 • 09:06 min • June 10th, 2013
June 10th, 2013 •
1, 1, 1
1Department of Biological Chemistry and The Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem

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MicroRNA har betydelige roller i hjernens struktur og funktion. Her beskriver vi en metode til at håndhæve hippocampus miRNA overekspression hjælp stereotaktisk injektion af en manipuleret miRNA-udtrykkende lentivirus. Denne fremgangsmåde kan fungere som en relativt hurtig måde at vurdere

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Behavior Neuroscience neurobiologi anatomi fysiologi Biomedical Engineering Bioengineering Molekylærbiologisk Institut Surgery sygdomme i nervesystemet Nucleic Acids nukleotider Nucleosides adfærdsmæssige test hippocampus indlæring og hukommelse microRNA stereotaktisk injektion morris vand labyrint mus dyremodel
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