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Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors
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Bioengineering
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JoVE Journal Bioengineering
Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

DOI:
10.3791/50396-v

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11:52 min

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June 18, 2013

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, ,
1Department of Biomedical Engineering,University of Southern California, 2Department of Biomedical Sciences,Cedars-Sinai Medical Center, 3Geffen School of Medicine,University of California, Los Angeles

Chapters

  • 00:05Title
  • 01:43Systemic Delivery In vivo
  • 02:53Fluorescence Imaging In vivo
  • 04:23Fluorescence Imaging Ex vivo
  • 05:23In situ Confocal Imaging of Tumors
  • 06:41Ratiometric Spectral Imaging and Analysis
  • 07:59Representative Imaging Results
  • 11:16Conclusion

Summary

Automatic Translation

Automatic Translation

This article details the procedures for optical imaging analysis of the tumor-targeted nanoparticle, HerDox. In particular, detailed use of the multimode imaging device for detecting tumor targeting and assessing tumor penetration is described here.

Tags

Keywords: HER2+ TumorNanoparticleHerDoxTumor-targetedCell Penetration ProteinDoxorubicinSelf-assemblyTumor TargetingTumor Cell PenetrationMultimode Imaging

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