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Neuroscience

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Genetic Manipulation of the Mouse Developing Hypothalamus through In utero Electroporation
 

Genetic Manipulation of the Mouse Developing Hypothalamus through In utero Electroporation

Article DOI: 10.3791/50412
July 24th, 2013

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Summary July 24th, 2013

Despite the functional and medical importance of the hypothalamus, in utero genetic manipulation of its development has rarely been attempted. We show a detailed procedure for in utero electroporation into the mouse hypothalamus and show representative results of total and partial (regional) hypothalamic transfection.

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