This paper demonstrates a protocol to characterize the mechanical properties of living cells by means of microindentation using an Atomic Force Microscope (AFM).
Thomas, G., Burnham, N. A., Camesano, T. A., Wen, Q. Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy. J. Vis. Exp. (76), e50497, doi:10.3791/50497 (2013).