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Neuroscience

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Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis
 

Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis

Article DOI: 10.3791/50870 14:58 min
February 13th, 2014

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Summary February 13th, 2014

Methods for the manipulation and analysis of NF-κB-dependent adult hippocampal neurogenesis are described. A detailed protocol is presented for a dentate gyrus-dependent behavioral test (termed the spatial pattern separation-Barnes maze) for the investigation of cognitive outcome in mice. This technique should also help enable investigations in other experimental settings.

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