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MACS纯化光感受器前体细胞的亚视移植到成年小鼠视网膜中
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JoVE Journal Medicine
Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina
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MACS纯化光感受器前体细胞的亚视移植到成年小鼠视网膜中

DOI:
10.3791/50932-v

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08:28 min

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February 22, 2014

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, , ,
1CRTD / DFG-Research Center for Regenerative Therapies Dresden,Technische Universität Dresden

Chapters

  • 00:05Title
  • 01:33Retina Dissociation
  • 03:21Cell Sorting Using Magnetic Associated Cell Sorting (MACS)
  • 05:07Transplantation of MAC-sorted Photoreceptor Precursor Cells Into the Mouse Retina
  • 06:39Results: Donor GFP+ Rod Photoreceptor Integration Into the Host Retina
  • 07:42Conclusion

Summary

Automatic Translation

Automatic Translation

细胞移植是治疗视网膜退化的一种策略，其特征是光感受器丧失。在这里，我们描述了一种丰富可移植光感受器及其亚视移植到成年小鼠的方法。

Tags

Subretinal TransplantationPhotoreceptor Precursor CellsMACSAdult Mouse RetinaVision ImpairmentBlindnessPhotoreceptor ReplacementCell IntegrationCell SortingCD73Rod Photoreceptor Precursors

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