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JoVE Journal
Medicine

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乳腺癌的一种新的转基因小鼠模型:转移性乳腺癌通过瞄准导管上皮与腺病毒Cre重组酶的启动
 
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乳腺癌的一种新的转基因小鼠模型:转移性乳腺癌通过瞄准导管上皮与腺病毒Cre重组酶的启动

Article DOI: 10.3791/51171-v 07:14 min March 26th, 2014
March 26th, 2014

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

活化的潜在的突变腺病毒Cre重组到乳腺导管系统的结果在一个临床相关的转移性乳腺癌。注册一个YFP的启动子可以让远端转移性肿瘤细胞的跟踪。这个模型是研究潜转移,抗肿瘤免疫力,而为设计新颖的免疫疗法治疗乳腺癌有用。

Tags

医药,第85,转基因小鼠,乳腺癌,转移,导管内注射,潜突变,腺病毒Cre重组
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