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JoVE Journal
Bioengineering

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Tissue Engineering of Tumor Stromal Microenvironment with Application to Cancer Cell Invasion
 

Tissue Engineering of Tumor Stromal Microenvironment with Application to Cancer Cell Invasion

Article DOI: 10.3791/51321
March 18th, 2014

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Summary March 18th, 2014

Tissue engineered fibroblast-derived native matrix is an emerging tool to generate a stromal substrate which supports epithelial cell proliferation and differentiation. Here a protocol applying this methodology to assess the impact of different stromal cell types on tumor cell biology is presented.

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