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Neuroscience

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Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection
 

Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders

Article doi: 10.3791/51853
December 4th, 2014 Usage Statistics

Summary December 4th, 2014

In this study, a novel platform to investigate intraneuronal molecular signatures of treatment response in bipolar disorder (BD) was developed and validated. Olfactory epithelium from BD patients was obtained through nasal biopsies. Then laser-capture microdissection was combined with Real Time RT PCR to investigate the molecular signature of lithium response in BD.

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