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Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
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JoVE Journal Medicine
Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

DOI:
10.3791/52036-v

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16:56 min

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August 30, 2014

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, , ,
1Departamento de Desarrollo Biotecnológico,Universidad de la República, 2Present Affiliation: Trinity Biomedical Science Institute,Trinity College Dublin

Chapters

  • 00:00Title
  • 03:21Sublingual Administration of the Therapeutic Agent
  • 05:59Preparation of Bacterial Suspension and Intranasal Challenge with Streptococcus pneumoniae
  • 08:02Tissue Collection and Sample Preparation for FACS Analysis
  • 14:40Representative Results
  • 15:22Conclusion

Summary

Automatic Translation

Automatic Translation

The present work illustrates the convenience of using sublingual immunotherapy to boost the innate immune response in the lungs and confer protection against acute pneumococcal pneumonia in mouse.

Tags

Keywords: Sublingual ImmunotherapySLITRespiratory InfectionsPneumococcal PneumoniaMucosal ImmunityLung ImmunityIntranasal DeliveryMouse ModelImmune Response Analysis

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